A key premise of the paper is that the regional level of planning is a particularly appropriate level for the integration of biophysical and socio-economic development issues.The UK, and the European Union leash (EU) more generally, have witnessed some important developments in regional planning practice over the last decade which have sought to en
Reproducible neuroimaging features for diagnosis of autism spectrum disorder with machine learning
Abstract Autism spectrum disorder (ASD) is the fourth most common neurodevelopmental disorder, with a prevalence of 1 in 160 children.Accurate diagnosis relies on experts, but such individuals are scarce.This has led leash to increasing interest in the development of machine learning (ML) models that can integrate neuroimaging features from functio
Anxiety, depression and HIV in older gay and bisexual men
Introduction Negative consequences of social homonegativity and HIV status among older gay and bisexual men in Portugal are still to be documented.Objectives This study seeks to evaluate depression and anxiety disparities among older gay and bisexual men, based upon their HIV status.Methods This is a quantitative, descriptive, comparative, and cros
Photobleaching Kinetics and Time-Integrated Emission of Fluorescent Probes in Cellular Membranes
Since the pioneering work of Hirschfeld, it is known that time-integrated emission (TiEm) of a fluorophore is independent of fluorescence quantum yield and illumination intensity.Practical implementation of this important result for determining exact probe distribution in living cells is often hampered by the presence of autofluorescence.Using kine
Low bias electron transport properties of the graphene-Ge2Sb2Te5 heterostructure device
We explore the performance improvement of ultra-scaled phase-change memory (PCM) device with graphene- Ge2Sb2Te5 (GST) heterostructure by means of first-principle simulations of electron transport.We compare the tunneling probability of single-barrier(SB) and double barrier(DB) heterostructures and show that the use of DB can have a significant imp